Mark S. Lyell, M.D.

Dr. Mark Lyell has been with South Mississippi Urology, PLLC, for nearly 28 years. Dr. Lyell began his private practice in urology in 1992. He is a graduate of the University of Louisville Medical School and performed his residency in urology at Oklahoma University. Dr. Lyell is certified by the American Board of Urology and a fellow of the American College of Surgeons.

He is also a member of the American Urological Association, American Association of Clinical Urologists, Mississippi State Medical Association, and Singing River Medical Society. Dr. Lyell is also a very active member in the community, previously serving on the Board of Directors for the Jackson County Chamber of Commerce. Dr. Lyell was also past Chief of Staff at Singing River Health System.

Dr. Lyell attends patients at our clinics in Ocean Springs, Pascagoula, and Biloxi.

Board Certification
American Board of Urology

Medical Degree
University of Louisville

University of Oklahoma

Areas of Expertise
Urology Cancer Treatment
Da Vinci Xi Robotic-Assisted Surgery
Prostatic Disease Treatment
Kidney Stones
Vasectomy Reversal
Erectile Dysfunction
UroNav Technology

Thank You for Being Our Patient

Thank you for seeing Dr. Mark S. Lyell at South Mississippi Urology, PLLC. We hope that you were happy with your experience and will leave us an online review! You may also message us privately via our online “Thank a Doctor” form! Go here to learn more: .



What Our Clients Say

Both, Dr. Lyell and Dr. Spencer Jr., are very friendly. Also, the staff is very welcoming and the facility is very clean. I trust these doctors when it comes to finding answers and knowing what is best for me and even my family! Thank y'all so much.

— Amber G.

They were very professional with my husband and I. We have been needing answers for questions for over a year and we finally were able to find some answers here. The facility is very clean. The staff is very friendly.

— Brandy SM.

Contact us

Make an appointment and visit South Mississippi Urology, PLLC

Pascagoula Office

2525 Telephone Road
Pascagoula, MS 39567
Map & Directions [+]
Phone: (228) 769-2069

Ocean Springs Office

1124 Oakleigh Road
Ocean Springs, MS 39564
Map & Directions [+]
Phone: (228) 875-3778

Biloxi Regional Office

147 Reynoir Street, Suite 306
Biloxi, MS 39530
Map & Directions [+]
Phone: (228) 432-1116
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